Figure 6. Effect of gene dosage on retinal ganglion cell number

Effect of gene dosage on retinal ganglion cell number. Red symbols are Rara cases, blue symbols are Rarb cases. A single heterozygous Rarb animal with a count of 83,200 has been dropped from the analysis. Age, sex, and body weight are not significant predictors of retinal ganglion cell number and for this reason the original counts were used in the regression against gene dosage. KO = knockout (-/-), HT=heterozygote (+/-), WT=wildtype (+/+).