Table 4 of
Lewis, Mol Vis 2001;
7:164-171.
Table 4. Rat lens gap junction activity from galactosemic and HAR-1 treated rats
Gap junction activity of normal and galactosemic rat lens was assayed by determination of the extent of dye transfer through the lens. Lenses were injected with 2.5 mg/ml Lucifer yellow (10 ml total volume) and the extent of dye transfer for 30 min at 25 °C was determined. The control group was on a normal diet, the galactose group was on a 40% galactose diet for 6 days, and the "galactose + HAR-1" group received HAR-1 at 100 mg/kg body wt/day, orally for 6 days. Dye transfer is from site of injection in mm.
Dye transfer Dye transfer Dye transfer Mean Experiment in lens 1 in lens 2 in lens 3 dye transfer ---------- ------------ ------------ ------------ ------------ Control 78.1 82.3 70.7 77.0 galactose 30.3 39.2 34.7 34.7 galactose 70.6 87.8 79.2 79.2 + HAR-1 |