Figure 7 of
Shaw, Mol Vis 2001;
7:6-13.
Figure 7. The rAAV vector for ribozyme delivery
Schematic of the rAAV vector used to express the ribozyme RNA in photoreceptor cells. TRs are inverted terminal repeats; P-opsin is a rod cell-specific opsin promoter; SS is a splice donor/acceptor site derived from SV40; Rz is the coding region for the ribozyme; PA is a polyadenylation termination signal; K-Neo is a thymidine kinase promoter followed by the neomycin resistance gene.