Figure 2 of
Zhou, Mol Vis 2001;
7:79-88.Figure 2 of
Zhou, Mol Vis 2001;
7:79-88.
Figure 2. Mouse and human promoter sequence
DNA sequence of about 400 bp upstream of the transcription start site (+1) of both mouse and human Lim2. The noncoding exon 1 is marked in brown. Sequences having high homology between mouse and human are marked in red, dark purple, green, purple, and blue.
MOUSE -380 -360 -340
GATCCTACC-GTACAAAGAACCCCTTGGCCTGACATGTCTAGATACCTATATCCACCCGT
| | ||| || || | | || | | | || |||| |
-A-C--ACCTGT-----GA-C---T---CC---C----C-A----CC-----CCAC---T
HUMAN-400 -380
-320 -300 -280
GCCATTGCTGCTTCCTGTCCCTTGAGCTGGGAAGCCCAGGTTGAACAATAAAACG-GTGT
||| | ||| |||| || || |||||| |||||||||||||| || |||
GCC-T-GCT-CTTCAGGTA----GA------AAGCCCTGGTTGAACAATAAA-CGCGTGA
-360 -340
-260
CTATC--T-A--CT--C-T-TAT-CTCTT-----TGTGTG-G-GT-T-T-TGC-T-T-T-
|| || | | || | | | | | | |||||| | || | | ||| | | |
CTCTCCCTGAATCTTGCGTGTGTGCGCGCGCCCGTGTGTGTGTGTGTGTGTGCGTGTGTG
-320 -300 -280
-240 -220
C-TG-T-A-AGAG-TCAGGATAC--CCAGGGTGG----G-G-A---CTGG-GAATAAAG-
| || | | | || || ||| | ||||||| | | | | |||| || || |
CGTGCTTACACAGCTC-GGACAAAGCCAGGGTTGCTTTGAGCAAGGCTGGCGAC-AAGGT
-260 -240 -220
-200 -180 -160
ACTGGGAAAT--GGGGAGGGTCACAGA---CAA-GAG-GT-TGATGGG-GCCCCTTTG-T
| |||| | ||||||||||||||| || ||| | || ||| ||||| | | |
ATTGGGT--TCCGGGGAGGGTCACAGAGGTCAGTGAGTGGGTGGGGGGAGCCCCCTGGAT
-200 -180 -160
-140 -120 -100
CCCCTGCTTCAGCAAATTCCATTGG-GGCCTCTGCT-G-CCACTGTGTTTCTGCCTGCTG
|| ||||||||| ||||||||| | ||||||||| | || ||| |||||||||||||
GCC-TGCTTCAGCGAATTCCATTTGAGGCCTCTGCCAGACCGCTGCATTTCTGCCTGCTG
-140 -120 -100
-80 -60 -40
GAAGC-TGCTAGGCCA-TGC-AGTCATTGTGT-GGTGAGGCTTAAGGGATTTCGGGGGAA
||||| |||| || | || | |||||||| || |||||||||||||||| |||| ||
GAAGCGTGCTGGGT-AGTGGGACCCATTGTGTAGG-GAGGCTTAAGGGATTT-GGGG-AA
-80 -60
-20 +1
CC-ACGAGG-CAGAGATGCCAGCAACCTGGCTCGGCTCAGTATCCA-CAGAGGGGCTGT-
|| | | || || ||| ||||| ||| ||||| ||||||| | || ||||||||| ||
CCTAAGGGGGCAAAGAGGCCAGTGACCAGGCTCAGCTCAGTCTGCAGCAGAGGGGCCGTC
-40 -20 +1
GGCAGAAGGCAGGGCTCAGAACAGACTCTGCCACTCAG
||||||||| ||||||| | ||| |||||| ||||||
GGCAGAAGG-AGGGCTCGGG-CAGGCTCTGCGACTCAG
|