Table 3 of
Schmidt, Mol Vis 2000;
6:287-293.Table 3 of
Schmidt, Mol Vis 2000;
6:287-293.
Table 3. APOE genotypes and alleles of familial cases and controls, by age and gender
Age- and gender-specific distribution of APOE genotypes and alleles for familial cases and controls.
Age (Years)
-----------------------------------------
Women Men
------------------- -------------------
<70 70-79 >79 <70 70-79 >79 Women Men Total
---- ----- ---- ---- ----- ---- ----- ---- -----
Familial cases
Number 28 40 24 11 20 6 92 37 129
% of all cases 21.7 31.0 18.6 8.5 15.5 4.7 71.3 28.7 100
APOE genotype (%)
e2/e2 0.0 5.0 0.0 0.0 0.0 0.0 2.2 0.0 1.6
e2/e3 10.7 7.5 12.5 18.2 10.0 0.0 9.8 10.8 10.1
e3/e3 85.7 62.5 75.0 54.6 65.0 83.3 72.8 64.9 70.5
e2/e4 0.0 2.5 0.0 0.0 5.0 0.0 1.1 2.7 1.6
e3/e4 3.6 22.5 12.5 27.3 20.0 16.7 14.1 21.6 16.2
e4/e4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
APOE-e4 carriers (%)
3.6 25.0 12.5 27.3 25.0 16.7 15.2 24.3 17.8
APOE allele (%)
e2 5.4 10.0 6.3 9.1 7.5 0.0 7.6 6.8 7.4
e3 92.9 77.5 87.5 77.3 80.0 91.7 84.8 81.1 83.7
e4 1.8 12.5 6.3 13.6 12.5 8.3 7.6 12.2 8.9
Controls
Number 123 67 9 73 78 22 199 173 372
% of all controls 33.1 18.0 2.4 19.6 21.0 5.9 53.5 46.5 100
APOE genotype (%)
e2/e2 0.0 4.5 0.0 1.4 0.0 0.0 1.5 0.6 1.1
e2/e3 11.4 9.0 22.2 12.3 12.8 13.6 11.1 12.7 11.8
e3/e3 57.7 59.7 66.7 54.8 64.1 81.8 58.8 62.4 60.5
e2/e4 2.4 4.5 0.0 2.7 0.0 0.0 3.0 1.2 2.2
e3/e4 24.4 19.4 11.1 26.0 21.8 4.6 22.1 21.4 21.8
e4/e4 4.1 3.0 0.0 2.7 1.3 0.0 3.5 1.7 2.7
APOE-e4 carriers (%)
30.9 26.9 11.1 31.4 23.1 4.6 28.6 24.3 26.7
APOE allele (%)
e2 6.9 11.2 11.1 8.9 6.4 6.8 8.5 7.5 8.1
e3 75.6 73.9 83.3 74.0 81.4 90.9 75.4 79.5 77.3
e4 17.5 14.9 5.6 17.1 12.2 2.3 16.1 13.0 14.6
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