Table 2 of
Schmidt, Mol Vis 2000;
6:287-293.
Table 2. APOE genotype and allele frequency distribution
Comparison of APOE genotypes and alleles of cases and controls, overall and by family history of cases.
Sporadic Familial All cases Controls
cases cases
----------- ----------- ----------- -----------
APOE genotype
e2/e2 2 (2.0%) 2 (1.6%) 4 (1.7%) 4 (1.1%)
e2/e3 13 (12.9%) 13 (10.1%) 26 (11.3%) 44 (11.8%)
e3/e3 58 (57.4%) 91 (70.5%) 149 (64.8%) 225 (60.5%)
e2/e4 4 (4.0%) 2 (1.6%) 6 (2.6%) 8 (2.2%)
e3/e4 21 (20.8%) 21 (16.2%) 42 (18.3%) 81 (21.8%)
e4/e4 3 (3.0%) 0 (0.0%) 3 (1.3%) 10 (2.7%)
Total 101 129 230 372
APOE-e4 carriers
28 (27.8%) 23 (17.8%) 51 (22.2%) 99 (26.7%)
APOE allele
e2 21 (10.4%) 19 (7.4%) 40 (8.7%) 60 (8.1%)
e3 150 (74.3%) 216 (83.7%) 366 (79.6%) 575 (77.3%)
e4 31 (15.4%) 23 (8.9%) 54 (11.7%) 109 (14.6%)
Total 202 258 460 744
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