Table 2 of
Schmidt, Mol Vis 2000;
6:287-293.
Table 2. APOE genotype and allele frequency distribution
Comparison of APOE genotypes and alleles of cases and controls, overall and by family history of cases.
Sporadic Familial All cases Controls cases cases ----------- ----------- ----------- ----------- APOE genotype e2/e2 2 (2.0%) 2 (1.6%) 4 (1.7%) 4 (1.1%) e2/e3 13 (12.9%) 13 (10.1%) 26 (11.3%) 44 (11.8%) e3/e3 58 (57.4%) 91 (70.5%) 149 (64.8%) 225 (60.5%) e2/e4 4 (4.0%) 2 (1.6%) 6 (2.6%) 8 (2.2%) e3/e4 21 (20.8%) 21 (16.2%) 42 (18.3%) 81 (21.8%) e4/e4 3 (3.0%) 0 (0.0%) 3 (1.3%) 10 (2.7%) Total 101 129 230 372 APOE-e4 carriers 28 (27.8%) 23 (17.8%) 51 (22.2%) 99 (26.7%) APOE allele e2 21 (10.4%) 19 (7.4%) 40 (8.7%) 60 (8.1%) e3 150 (74.3%) 216 (83.7%) 366 (79.6%) 575 (77.3%) e4 31 (15.4%) 23 (8.9%) 54 (11.7%) 109 (14.6%) Total 202 258 460 744 |