Table 1 of
Wong, Mol Vis 2000;
6:184-191.Table 1 of
Wong, Mol Vis 2000;
6:184-191.
Table 1. Clusterin expression in the primate eye
Summary of reports of clusterin expression in the primate eye. An asterisk ("*") in the source column indicate that the finding is reported herein. This report includes new observations of clusterin expression in eyelid, iris, lens, limbus, orbital muscle, cultured RPE, sclera, and trabecular meshwork. (W = Western analysis, IH = Immunohistochemistry; NA = Not applicable; ISL= In situ localization; N = Northern analysis)
RNA/Protein
Species (Method) Expression Status Source
------- ------------- ------------------------------ ------
Aqueous
Human Protein (W) protein detected [17]
Ciliary Body
Human Protein (IH) protein detected [17],*
Monkey mRNA (N) mRNA detected *
Monkey Protein (W) protein detected (HMW, 80 kDa) *
Cornea
Monkey mRNA (N) mRNA detected
Monkey Protein (W) protein not detected
Human mRNA (ISL) mRNA detected [19],*
Human Protein (IH) protein detected [19],*
Cornea (epithelium)
Human mRNA (RT-PCR) mRNA detected [19]
Human Protein (W) protein detected [19]
Eye lid/Skin
Human Protein (IH) protein detected *
Iris
Monkey mRNA (N) mRNA not detected *
Monkey Protein (W) protein not detected *
Lens
Monkey mRNA (N) mRNA detected *
Human Protein (IH) protein detected *
Limbus
Monkey mRNA (N) mRNA detected
Monkey Protein (W) protein detected (HMW, 80 kDa) *
Orbital Muscle
Monkey mRNA (N) mRNA not detected *
Monkey Protein (W) protein detected (80 kDa) *
Retina
Human mRNA (ISL) mRNA detected [17]
Human mRNA (N) mRNA detected [18]
Human protein (IH) protein detected [20]
Monkey mRNA (N) mRNA detected *
Monkey protein (W) protein detected (80 kDa) *
RPE
Human mRNA (ISL) mRNA detected [17]
RPE (cultured)
Monkey mRNA (N) mRNA detected *
Monkey Protein (W) protein detected (80 kDa) *
RPE/choroid
Monkey mRNA (N) mRNA detected *
Monkey Protein (W) protein detected (HMW, 80 kDa) *
Sclera
Monkey mRNA (N) mRNA detected *
Monkey Protein (W) protein detected (HMW, 80 kDa) *
Trabecular Mesh
Monkey mRNA (N) mRNA detected *
Monkey Protein (W) protein not detected *
Vitreous
Human Protein (W) protein detected [17]
Monkey Protein (W) protein detected (80 kDa) *
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