Figure 5 of
Wistow, Mol Vis 2000;
6:79-84.Figure 5 of
Wistow, Mol Vis 2000;
6:79-84.
Figure 5. The 5'- region of the CRYGS gene
Human sequences are compared with those of the mouse crygs gene. Consensus transcription factor binding sites are indicated: MARE in pink, homeobox binding (Hb) sites in orange, SRY/Sox site in brown, AP-1 in purple, NF-E2 in blue, and TATA box in green (see text for details and references). Sequences are numbered relative to the transcription start site determined experimentally in mouse [7]. Exon 1 is shown in red.
-264 gagagactcttttgttcttaatttttacaac-tttgtctgggttttggtttc-ttgactc Human
|||| | |||| ||| | ||||||| ||| |||| ||||||||||| | | |||| ||
-259 gagaaaatcttg-gttttgaattttttaaacgtttggctgggttttgggtgccttgattc Mouse
MARE Hb
-206 agcaaagtctgtaatgcagccctgcttggtaagcattaaaggcggtactgaagctttcct
|||| || || ||||||| ||| || ||||||| ||| | || || ||| ||||
-202 agcagagcctacaatgcagtagggctgggcgagcattacaggggccacaga-gctctcct
Hb SRY AP-1
-146 ttattttataatcccagttgttttttctagaaaccatcaatagcgtctaaatgactgact
|||||| ||||||||| |||||||| |||| |||||||||||| |||||||||||||||
-143 ttatttcataatcccaattgttttt-ctagcaaccatcaatagactctaaatgactgact
NF-E2 TATA
-86 caatttttggatcctattctcatgactaagcaaatgtttgactgaaaccagcccatataa
||| |||||||||| ||||||||||||||||| |||||||| | ||| || |||||
-84 caaattttggatccaattctcatgactaagcagatgtttgatttgaactgccctctataa
Exon 1
-26 atgtcactgtgcctctaactctctgtagccattcctgaatttctttcagcactgggaaaa +34
||||| || ||||| | | || ||| || | |||| || ||| |||| | || | ||
-24 atgtccctctgcctgt-agtc-ctggag-ctgccctggatctctctcagtagtgcgggaa +33
M S K T G T K Intron 1
ccagtctatgcaccaaaaATGTCTAAAACTGGAACCAAGgtaagtagtcatattgatttt +94
|| || ||||| | |||||||||||||||| |||||||||
tcaacctttgcacatacaATGTCTAAAACTGGAGGCAAGgtaag---------------- +77
M S K T G G K
tagcctacccgcttttcacctaatgatgcattcaacacacagaaaagcttttgcttcttt +154
|| | | || ||| | | | | ||||| || | |||| ||||||| |
-----taactgtttctcatccaggggcacgttcaa-----agcagagctgttgcttcact +127
gcctagaggtgagtatgatagtggttagagaactgggattgagagagaagattaagaaat +214
||| ||| |||||| ||||| | | || | | |||||||||| | |||
gccctgagatgagtaaactagtgctcgagggacaatcctggggagagaagatgga-aaag +186
|