Figure 1. The pedigrees of two unrelated families with fundus albipunctatus

Both families show an autosomal recessive inheritance pattern with two affected siblings. Family 1002 (A) is of Greek descent. The parents of the effected daughters are seventh cousins in family 1002. Family 1006 (B) is of German descent. The asterisks indicate family members with known RDH5 genotype. The arrow indicates the proband in each family.