Table 1 of
Seigel, Mol Vis 1999;
5:4.
Table 1. A Comparison of Retinal Culture Systems
Summary the major differences between the basic types of retinal cultures discussed in the text.
Characteristics of Retinal Cell Cultures Primary Cultures Retinoblastoma Cultures Engineered Cell Lines --------------- ---------------------- ----------------------- --------------------- Examples Explants, Reaggregates Y79, WERI-Rb1, KGLDMSM, R28 Monolayers FMC-Rb1, RB355-7 rMC-1 Lifespan Finite (2-4 weeks) Indefinite Indefinite Freezer No Yes Yes storage Phenotypic Excellent Immature Variable Marker Expression Growth Post-mitotic or Highly proliferative Mitotic Characteristics slow-growing Tumor-forming None High Range: none to high ability |