Table 1 of
Seigel, Mol Vis 1999;
5:4.Table 1 of
Seigel, Mol Vis 1999;
5:4.
Table 1. A Comparison of Retinal Culture Systems
Summary the major differences between the basic types of retinal cultures discussed in the text.
Characteristics of Retinal Cell Cultures
Primary Cultures Retinoblastoma Cultures Engineered Cell Lines
--------------- ---------------------- ----------------------- ---------------------
Examples Explants, Reaggregates Y79, WERI-Rb1, KGLDMSM, R28
Monolayers FMC-Rb1, RB355-7 rMC-1
Lifespan Finite (2-4 weeks) Indefinite Indefinite
Freezer No Yes Yes
storage
Phenotypic Excellent Immature Variable
Marker
Expression
Growth Post-mitotic or Highly proliferative Mitotic
Characteristics slow-growing
Tumor-forming None High Range: none to high
ability
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