Figure 13 of
Winkler, Mol Vis 1999;
Figure 13. Dimethylfumarate protects cultured RPE cells from oxidative injury
A 24 h pretreatment with 0.1 mM dimethylfumarate (DMF) protects cultured human RPE cells from oxidative injury associated with a toxic dose of tertiary butyl hydroperoxide (tBHP). Viability of cells was determined by measuring the extent of leakage of lactic acid dehydrogenase from the cells into the incubation media.