Table 1 of
Takemoto, Mol Vis 5:2, 1999.Table 1 of
Takemoto, Mol Vis 5:2, 1999.
Table 1. Deamidation of Asn-101 & Gln-50
Donor Age (yr) Deamidation Asn-101* Deamidation Gln-50* Deamidation Gln-6
-------------- -------------------- ------------------- -----------------
Normal lens:
59 52.6 ± 1.3 16.7 ± 1.3 Not Detectable
61 51.8 ± 0.8 15.1 ± 2.5 Not Detectable
64 54.1 ± 0.7 14.2 ± 2.9 Not Detectable
66 54.7 ± 2.9 14.2 ± 3.3 Not Detectable
71 53.8 ± 2.5 18.9 ± 6.9 Not Detectable
AVERAGE ± S.E. 53.4 ± 1.2 15.8 ± 2.0
Cataractous lens:
59 57.0 ± 2.5 21.6 ± 3.5 Not Detectable
60 46.1 ± 4.5 14.8 ± 1.7 Not Detectable
60 49.2 ± 5.3 14.8 ± 1.3 Not Detectable
65 56.1 ± 2.2 15.7 ± 3.0 Not Detectable
70 52.5 ± 3.2 17.1 ± 1.0 Not Detectable
AVERAGE ± S.E. 52.2 ± 4.6 16.8 ± 2.8
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*Percent deamidation as described in Methods, average of three determinations ± standard error.