Figure 4. Retinal rescue mediated by lactose: morphology and immunolocalization patterns.

A. Lactose permitted organization of the photoreceptor outer segments in the absence of the RPE. Individual outer segment profiles in a stacked orderly array are present (arrows). B. Opsin immunopositive labeling is present in a pattern similar to that noted under control conditions in which the RPE was present (arrows). C. rds/peripherin was localized to the periphery of the outer segment (arrows). Bar = 10 µm.