Figure 1 of
Tao, Mol Vis 4:25, 1998.
Figure 1. Amino acid sequence of mouse RGR aligned with that of human and bovine RGR
For comparison, only amino acid (one-letter code) sequence differences in the human and bovine proteins are shown, and identities to mouse RGR are indicated by dashes. The sequence of the carboxyl terminal peptide used to generate the mcDE5 antibody is shown in blue, and numbering of the amino acid sequence is on the right. A conserved lysine residue, which is homologous to the retinal attachment site of visual pigments, is shown in red. The nucleotide sequence of the mouse RGR cDNA is deposited under GenBank accession number AF076930.
MAATRALPAGLGELEVLAVGTVLLMEALSGISLNGLTIFSFCKTPDLRTPSNLLVLSLAL 60 --E-S---T-F---------M---V-----L---T----------E----CH-------- --ESGT--T-F-------------V-----L---I---L------E-----H-------- ADTGISLNALVAAVSSLLRRWPHGSEGCQVHGFQGFATALASICGSAAVAWGRYHHYCTR 120 --S----------T--------Y--D---A------V-------S---I----------- --S----------T--------Y------A------V-------S-----------F--- RQLAWDTAIPLVLFVWMSSAFWASLPLMGWGHYDYEPVGTCCTLDYSRGDRNFISFLFTM 180 S----NS-VS------L------A---L---------L---------K-----T------ SR-D-N--VS--F---L------A---L---------L---------------T------ AFFNFLVPLFITHTSYRFMEQKFSRSGHLPVNTTLPGRMLLLGWGPYALLYLYAAIADVS 240 S----AM-----I---SL----LGK----Q------A-T---------I-----V----T ------L-----VV---L----LGKTSRP----V--A-T---------------T---AT FISPKLQMVPALIAKTMPTINAINYALHREMVCRGTWQCLSPQKSKKDRTQ* mouse 291 S--------------MV----------GN------I--------RE----K* human S--------------AV--V--M----GS---H--I-------RREHS-E-* bovine |