Figure 3. TIM-barrel structure of ALR2

The movie shows the backbone folding of ALR2. The ribbons in magenta show eight a-helices surrounding a core of eight b-strands (in yellow) all in parallel orientation. The arrows on the b-strands point from N- to C-terminus. The active site is located on the C-terminal side of the b-strands and is associated with three loops (in white and blue).

Note that the slide bar at the bottom of the quicktime movie can be used to manually control the flow of the movie. If you do not want to or are unable to view the movie, a representative frame is included below as a still image.