Figure 1 of El-Kabbani, Mol Vis 1998; 4:19.


Figure 1. The polyol pathway

Aldose reductase, the first and rate limiting enzyme of the polyol pathway, catalyzes the NADPH-dependent reduction of glucose to sorbitol. The pathway is completed by the second enzyme of the polyol pathway, sorbitol dehydrogenase, which converts sorbitol to fructose.

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El-Kabbani, Mol Vis 1998; 4:19 <http://www.molvis.org/molvis/v4/a19/>
©1998 Molecular Vision <http://www.molvis.org/molvis/>
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