Figure 3 of
Kennedy, Mol Vis 4:14, 1998.Figure 3 of
Kennedy, Mol Vis 4:14, 1998.
Figure 3. Mouse CRALBP Gene Sequence
The determined sequence (6855 nucleotides) of the 129/SvJ mouse CRALBP gene is shown with 5' flanking regions and introns in lower case letters and exons in upper case letters. Translated sequences are in green. Based on homology with the human CRALBP gene, the mouse transcription start site is numbered +1. The translation start-site (ATG) in exon 2, translation stop-site (TGA), polyadenylation signal (AATAAA) and terminator sequence (CTTGTGTC) are in red.
The Genbank accession numbers for the sequences reported are: AF084638 (5' flanking regions and exons 1-3); AF084639 (exon 4); AF084640 (exon 5); AF084641 (exon 6); AF084642 (exons 7 and 8).
cc ctttgctagc actgagaccc tttaatacgc -3901
ctcctcatgt tgtggggacc ccttaaccat aaaattattt ttgttgctcc -3851
atcataacta taattttgtc acctttatga atcataatgt aaatatctga -3801
tattcaggat atctgatatg caactcttgt gaaagggtcc atcaaccacc -3751
ccatccccca ccctcagtga tcatgaccca caggttgggt ctaggcagcc -3701
ctctcctgta agactctggc cagccttagc ttacagggga ttccctgagt -3651
gaacagcaca gagccgaaaa tcgatgcaaa aagcaagagg aatttattgc -3601
tccaacatgt tggggtcgcc ctgcacatga agagagagac cgaccacagg -3551
cagcccttcc tttacagctt ctccaggcag cagccattag gcacaatatg -3501
attggcagaa cagtatgact tttaaactga ttggtctata gggaatgagg -3451
taggtggcca acagtatctc tgagcctccc ctacccgccc gcaggtggcc -3401
agtggttggt ccctcctccc ggtctgagga atgtaattag ccccttcctt -3351
ccggagggga tgggtgcgtt ctttaagacc tttctcttcc aggaggggag -3301
gggtctggtg gaattttcta aagtacctga gctgacctct tcactccaac -3251
tagaccatgt catggtagtc ctcttggtac acagggatgc ttggtgatga -3201
atcacagagc ctcttagcag ctgggactct tacctcccat gagcatcaca -3151
gccagggagg ttctttgggc ataacagcat gccacagcct aggtgaatta -3101
accaatagaa aatcattctc tcggaatctc ggtagttgga ggtctaagat -3051
caaggtatta tcctttggtg tcacctcctt atcttataga taaaccctga -3001
actgtggctg gatttcagag aacgacctgt gcacatgagc tcaaccctac -2951
cctgagcaca tggaggagag agaaccagga ccaaaggtgg gctgcttggg -2901
tccagactga agatgaattt aattacagac aactatctgt ggtggaagta -2851
gggatctccc ggacattgga ggcccccaca gagatctaaa ggatgtgtat -2801
ccctcatacc ccggtgataa accaaggcag agtctgggtg ctcctttgac -2751
tgttggatgc attcccttag cctgggtgct cactggctct ccattcactg -2701
ggtacaactc agaactcccc agaatacttc ccagggattg ggcagctaag -2651
cccctgaagt gggtactttg catctcagga ctttccccac agcttcagct -2601
ggctctctag tcatcccagt tctcagaggg gactgagtca tgtcgtggtg -2551
acataaccac actgaaaaaa gtgcagtagc aaggacagaa agtcggacaa -2501
gggagatctg ctgaggcccc acacccatcc cctgcttcct tgcctttgcg -2451
aggtagagat cggcagagat cggagggtca gggtacctag caagtcctcc -2401
gctgctcagc ctcgcccgct ccatttccct ctgccacatg ggacagtgga -2351
ccataggcct gggttgcagc aatgatcaca tttataattt ctcttcactt -2301
ctctatatgt cctgcccttt gtgaagaagg agtagtctcc caggcccccc -2251
tgcctcccag tttgagaagc gagatggcag ggaaatgaga cggggctggc -2201
ccagatccag tgaagtggct tccacatggc tgaacagaga gctccaagca -2151
ggagctcaca aagcagggct ttgatggtag ccccgcaggc cgggcctctc -2101
ccctctccct cagggtgctt cacttgcttc attctgggcc tcctgtgagc -2051
ctgactgaat gggaaacggt gggcctgaga agttccttgt gacacactaa -2001
tcccagcttg ctgacctgac cacaccccca aagaaagcag cctcccgagc -1951
tccagaacaa ttcaggcatc cagtagcccc caagaaagag ctgtcaggta -1901
agtcagtaac aaggcctggc tgggccagtg agtataagaa agagtgtgtg -1851
catgggagcg gggtaaatga tcagggatgg gtggcgaaca ccacgtctca -1801
gattgcttgg accggcctgt aaaggcgtac gccatttccg cagggtgaga -1751
cagaccgatc cacgggcaga cgcaacacat acgaatgtgg attacctaac -1701
tcaattagaa tggcaggtga tcaaatactc tttatgccct agtattggta -1651
attaattgta ctttatttgc taattctaaa tgccggagaa catcgatgtg -1601
gagatagggg tagcatgttt ttattacata catgcctaca gctaatgggt -1551
aagaacattt ttaaaataag agataagtgc ttctccgtgc tgacgttaat -1501
cttgcacttc taagatctgg gacttgggct gctgatctgc acatttggct -1451
agggataatg cactaatacc tctcgagtct tgctttgctt tgtttgcttg -1401
aggcagggtt tctctacgta gccctagcta tcctggaact cactatgaag -1351
aacagactgg cttcaaaatc agagattccc ctagacactg ggattaaaga -1301
tgcgtaccac tatacccagc ttttgctttt cgtttttttg agatagagtc -1251
tcatgtagca caggctggtt ttgaattaac tatgtagcca aggataacct -1201
taactaagga ttctcttgcc tctatctttt tttttctttc ctttttaaaa -1151
attactagat attttctttg tttacatttc aaatgttatc gcctttccta -1101
gtttcctctc caaaagtccc ctataccctc acccccgccc tgctccccaa -1051
cccacccatt tctgtttcct ggccctggca ttcccctgta ctggggcata -1001
taatcttcgc aagactaagg gcctctcctc ccattgatgg ccaactaggc -951
catcttctgc tacataagca gctagagaca caagctctgg ggggtactgg -901
ttagttcata ttgttgttcc tcctataggg ctgcagaccc cttcagctcc -851
ttgggtactt tctctagctc cttcgttggg gaccctgtgt tccatcctat -801
agatgactgt gagcgtccac ttctgtattt gccaggcact gcttttgcct -751
ctatcttgca agttctggga atacagatgt gtgccacaac agtcaactct -701
tggtctttac acccacatat ctggatgtct gtctactatc caaagagatg -651
gcttgtactt gattcttgtg ggtagatccc agcccccaag aattccctgg -601
tcctttgggg gctgtggtag ggaagggata ggccctcaga tattctctga -551
gatcctcaag tttcagtgta caaattgggt taatctcagt gctagcaaag -501
ggagaaaaga ctgttgtcga tcaggagtcc tctctcggtt atgtcacaga -451
accctgtggt cctcacagcg gtcacttttg gtagatatta ttatccttcg -401
ttggctctca atctcagaag gattaaatac cttgcctatg gtcacacagg -351
tggtaaaagt cagattcaaa ttcagatctc tctaacctat aaggtttctg -301
tcaccagctc ccccagggac tttgcaaaga gatgacttgg cttgaggcaa -251
agagacttag tgtcaggtgg atacaggttc aagtcctagc ttaaatacca -201
actatgcgta agtgaccgag ctgaccaatg gaacctagcc acaggcagaa -151
acagaatgta aagatgttca cagtcactgg ggacatttag gtcttggagg -101
agaaaatctg gaaatgtggg tcatgatgga tatctgttct ggtggcccag -51
aaatctatgc tggtgtatat tatctaatta catattaatc cttctatccc -1
Exon 1
AACAAGGGAC GGTCAAGACT CGGATGAAAT CACACAACTT GCAAGTGTGA 50
GAGACAGCAT TGCAATCCAG GCCCCACACC CTGCTGCCCC AAGCTGCTTC 100
TTGGTGTCTA CAGAAGTCAC AACTTAGgta agtatccttg ggctctgtga 150
ccttggacca gtcacttact ctcctggccc tgttttcccc ttaaataaaa 200
caggagtgga gctgccatgc tcgtgtctga gttaacgaat ttagaagtcc 250
ttagaatgtt gtaaacctct gtaacaaaga cccaggtctg attatataac 300
tgctcaccat ggctcctaag aatgaatgcc ctgggtatgg agccatccac 350
taggtggaga ggtttctggg gtgcacattt gtactgggga agcaaggcta 400
cagagaagaa gagagattgc cttacactgc agtgagctga ccttgcagct 450
gagaatgggg cccaattctg gtttgttttt ggttagccac agctgaagac 500
tacttagtgt attggtagta tgctccctcc aaatgcagtg ttcccaaagt 550
atagcccagg aaacaagtcc ttcagagcta ggtagggaag gagggctcta 600
attttagtcc tctggttaga ctcacagggg ccaacactcg tctatatttc 650
tgaccaatca gctagctgtt gggagggact tgaatgcttg agatccactg 700
Exon 2
ttctgagaca aacacaaaat agtttctcta atatcactgc agTCTTGACT 750
TCTTTGACTG CTGGACAAAG GCTACCCGGA GAGACCAGGG CAGAGCAAAC 800
AGGTTCTTTC TCTCCCCCCT TCAGTGTCTT CAAGAGGCAG TATGTCAGAC 850
GGGgtgagta tcttgggctc ttcatccctt cttcccttcc tccccacacc 900
tcaacaatct ctctggggcc ccgacctacc aaagggagga gactgagcac 950
agatcttggc caaaggcact gtgcaaaccc atttgccagt tgttctggct 1000
Exon 3
gccaagggct gagctgtccc accttctatg actcctttcc gaccagGTGG 1050
GCACTTTCCG CATGGTTCCT GAAGAGGAGC AGGAGCTCCG AGCACAACTG 1100
GAGCAGCTCA CAACCAAGGA TCATGGTCCT GTCTTTGGCC CATGCAGCCA 1150
GCTGCCCCGC CACACTTTGC AGAAGgtgag gtggc..... .......... 1185
Exon 4
cgtgttctag GCCAAGGATG AGCTGAATGA AAAGGAGGAG ACCCGGGAGG
AAGCGGTGAG GGAGCTACAG GAGCTGGTAC AGGCACAGGC AGCTTCTGGC
GAGGAATTGG CCCTGGCAGT GGCTGAGAGG GTGCAGGCAA GAGACAGCGC
CTTCCTCCTG CGCTTCATCC GTGCCCGCAA GTTCGATGTG GGTCGTGCTT
ATGAGCTGCT CAAAGgtaag gcct...... .......... ..........
.......... .......... .......... .......... ..........
Exon 5
ctccttccag GCTATGTGAA CTTCCGCCTC CAGTACCCTG AACTCTTCGA
TAGTCTCTCC ATGGAGGCTC TCCGCTGCAC TATCGAGGCC GGATACCCTG
GTGTCCTTTC CAGTCGGGAC AAGTATGGTC GAGTGGTTAT GCTCTTCAAC
ATCGAAAACT GGCACTGTGA AGAAGTGACC TTTGATGAGg tcagccgg..
Exon 6
ATCTTACAGG CATATTGTTT CATTTTGGAG AAACTGCTGG AAAATGAGGA
AACCCAAATC AACGGCTTCT GTATTGTTGA GAACTTCAAG GGCTTCACCA
TGCAGCAGGC AGCAGGGCTC CGCCCCTCGG ATCTCAAGAA GATGGTGGAC
ATGCTCCAGg tgaggcctc. .......... .......... ..........
Exon 7
gtcattgcag GATTCATTCC CAGCCAGGTT CAAAGCTATC CACTTCATCC
ACCAGCCATG GTACTTCACC ACCACCTATA ATGTGGTCAA GCCCTTCTTG
AAGAACAAGC TGCTACAGAG Ggtgagtgtg tggctgcctc ccaacctttc
caaagaatga tcccaatttg ggtgaataat cctggacagc accacaagga
ggctgtagag agagacgtca cgtgacaaag atgggaggct gtgccttggt
ctcccctccc ccatccttgt gctcagttgc cctgctccct tgtctgcag
Exon 8
GTCTTTGTTC ACGGAGATGA CCTGGATGGC TTCTTCCAGG AGATTGATGA
GAACATCCTG CCTGCTGACT TTGGGGGTAC ACTGCCCAAG TACGACGGCA
AAGTTGTTGC TGAGCAGCTC TTTGGTCCCC GGGCTGAAGT TGAGAACACA
GCCTTATGAG GAGATGCCCT GCCATGGGAT CCGTATTAGC ATCCCAGTCC
TTCTTCAGCT TTCCTGAACC CAAGTCCGGG GACAGGAATG CCTGAAGGGA
CTGTTTTCCC AGACTTCCCT AGGTTTAGGA ACGCTCTAGT GGCACCTCAT
CCCAAACCGA CCTAGAGGGC AGTGAGGCAG GGGAATGCCT TTCATCGGGA
GATATGTGGG GCAGTTAAAT TCCCACCTGC CTCTGCAGTT ACAGGGCAGT
GACTCTGAGA GAAGTTGGAT TTCAAAGACT AATTAGGCTT CTCCGTGATT
TCCTTTGTAA TCGCTTTGAT ACTTAGGGCG TGGAAGGCAG AGTTAAAGGC
ATACTTGCAA TTCAGTAAAA AGAAGAAAGA GAGGGGCTTG AAGCTCTGAT
GATCTTAACA GCAGTAGGCA GATAAGGGGT TTCCCACCCA GGATTCCAGG
GAGGGGCCAG CAACCTTAGC ACAGTTGCTG ATGAATACTC TAGTAGCTAA
GAGCTCTGGA CTCTGTCCAG GGTGGAGGTC ATGTCCCTTC CTCTCCACCC
ATCTTGGATG TGATCCTTGG TGCTGGGGCC CCCATTCACT AGATGCTGTA
GGCTTTGTTG TATGGTTTTA CTTAAATGTA CCTTTGACAT CTTCCCCGAA
CACTCTCAGT TCTTATTAGG CAAATAAAAC CGTTCTTTGT CTTGTGTC
|