To access the data, click or select the words “Appendix 6.” Clinical feature of KERA, CHRDL1, ZNF469 and PRDM5 (Age stratification). (A) Male versus female ratio for three genes by onset age (CHRDL1: X-Linked recessive and no female patients reported). (B) BCVA for four genes by onset age. BCVA=best-corrected visual acuity; CI=confidence interval; p<0.05: statistically significant differences; In Fisher's exact test, Cramer's V:0 (no association) to 1 (perfect association); In Kruskal–Wallis test, H (number of groups −1) rises as group differences become more distinct; ε²: 0 (no difference) to 1 (complete difference); * represents insufficient data for statistical analysis.