Appendix 11 of
Ulker-Yilmazer, Mol Vis 2026; 32:281-306.
Appendix 11. Supplementary Figure S8: Fundus spots appear to correspond to hyperreflective spots overlying the RPE and to subretinal microglia on the apical surface of the RPE.
To access the data, click or select the words “Appendix 11.” A-E: A fundus photo showing fundus spots in a 15-month-old Bicdl1 KI mouse (A) is overlayed on the Spectralis infrared image (B) accompanying the OCT in order to register the vessels and ensure the two images are at the same magnification and location. C) A magnified view of one of the fundus spots (red arrow) is shown. D) The OCT on the exact same location shows a hyperreflective spot overlying the RPE (red arrow). E) The same infrared image is shown separately in order to highlight that the vessels (red ovals) show the exact same magnification and orientation as the fundus photo. F) Another example of a fundus spot showing as a hyperreflective spot over the RPE. G,H) Representative images of Iba1 staining in 15-month-old WT (G) and Bicdl1 KI (H) retina sections. Subretinal microglia located on the apical surface of the RPE are seen in the KI retina section (white arrow). Scale bar = 100 µm