Figure 1. Healthy and DAMD cybrids show no differences in mitochondrial bioenergetics. Bioenergetic analysis of healthy and DAMD cybrids (A) showed no difference in basal (B) or maximal OCR (C), RCR (D), or proton leak (E). Interestingly, maximal respiration was always nearly 200% of basal OCR, suggesting conserved mitochondrial efficiency (F). ΔΨm was assessed with a JC1 assay and showed no difference between healthy and DAMD cybrids (G). Ten uM FCCP was used as a negative control. Healthy Cybrids: n=4, DAMD Cybrids: n=4.