Molecular Vision: Ye, Mol Vis 2025; 31:539-552. Table 2

Table 2. Cycloplegic changes in refractive and biometric parameters in cynomolgus macaques by myopia type.

Variables	Non-myopia		Pseudomyopia		True myopia		Pre-post differences
Variables	Pre	Post	Pre	Post	Pre	Post	Non-myopia	Pseudomyopia	True myopia	P
SR (D)	0.50 (0.25, 1.08)	1.25 (0.83, 1.75)*	−0.25 (−1.25, 0.25)	0.75 (0.25, 1.25)*	−0.75 (−2.33, −0.25)	-0.25 (−1.5, 0.5)*	−0.75 (−1.25, 0)	−1.5 (−1.75, −0.5)	−0.83 (−1.5, 0)	0.006^†
CR (D)	−0.75 (−1.25, −0.5)	-1.25 (−2, −0.75) *	−1.5 (−2.33, −0.50)	−1 (−1.75, −0.75)	−1.42 (−2.83, −0.5)	−2.5 (−3.75, −1)	0.42 (−0.25, 0.75)	0 (−1.5, 0.75)	0.50 (−0.75, 1.67)	0.025^†
SEM (D)	0.25 (−0.13, 0.63)	0.75 (0.13, 1.25)*	−1.13 (−1.75, −0.75)	0 (−0.13, 0.75)*	−2.25 (−4.04, −1.42)	-1.42 (−2.75, −0.88)*	−0.50 (−1, 0.13)	−1.42 (−2.25, −0.92)	−0.50 (−1.38, 0.21)	<0.001^†§
CP (D)	58.54±1.85	58.49±2.12	58.89±2.13	58.56±1.95	59.75±2.08	60.37±2.34*	0.05±1.16	0.33±1.16	−0.62±1.36	0.004^‡§
CCT (μm)	442.22±28.46	453.78±30.12*	449.09±26.31	453.77±36.83	444.97±36.46	458.65±39.42*	−11.55±14.63	−4.69±23.39	−13.68±13.35	0.06
ACD (mm)	2.62±0.13	2.68±0.14*	2.60±0.16	2.68±0.17*	2.66±0.16	2.74±0.16*	−0.06±0.03	−0.07±0.04	−0.09±0.03	0.005^‡
LT (mm)	3.05±0.11	3.02±0.12*	3.08±0.14	3.03±0.13*	3.04±0.14	2.99±0.14*	0.03±0.03	0.05±0.04	0.05±0.04	<0.001^†‡
AL (mm)	17.28±0.54	17.27±0.54	17.40±0.48	17.40±0.49	17.62±0.81	17.62±0.81	0.01±0.05	0.01±0.07	0±0.03	0.466

Abbreviations: SR, spherical refraction; CR, cylinder refraction; SE, spherical equivalent; CP, corneal power; CCT, central corneal thickness; ACD, anterior chamber depth; LT, lens thickness; AL, axial length. Data are presented as mean ± standard deviation or median (interquartile range). * Calculated using the pair test. † Pairwise comparisons between the non-myopia and pseudomyopia groups. ‡ Pairwise comparisons between the non-myopia and true myopia groups. § Pairwise comparisons between the pseudomyopia and true myopia groups.