Molecular Vision: de Freitas Cenachi, Mol Vis 2025; 31:526-537. Table 1

Table 1. Association between SD-OCT features and visual acuity in a nonsyndromic retinitis pigmentosa cohort.

SD-OCT features	Number of eyes analyzed (sample %)	Mean visual acuity (LogMAR)	p
Ellipisoid zone in central macula			<0,001
Preserved EZ	28/65 (43,1%)	0,24±0,14^ⱡ
Disorganized EZ	26/65 (40,0%)	0,49±0,35^ⱡ
Not detected EZ	11/65 (16,9%)	0,84±0,42^§
Elipisoid zone in perifoveal macula			0.212
Preserved EZ	2/65 (3,1%)	0,36±0,25
Disorganized EZ	13/65 (20,0%)	0,25±0,13
Not detected EZ	50/65 (76,9%)	0,49±0,39
Hyperreflective foci (HRF) in central macula			0.236
Absence of HRF	49/65 (75,4%)	0,40±0,37
Presence of HRF	16/65 (24,6%)	0,58±0,30
Hyperreflective foci in perifoveal macula			0.095
Absence of HRF	30/65 (46,2%)	0,32±0,29
Presence of HRF	35/65 (53,8%)	0,55±0,39

p - descriptive level of the mixed-effects regression model (p - mixed linear model); statistically significant finding is represented in bold. § and ⱡ indicate significantly different means based on ad hoc multiple comparisons with Bonferroni correction. The features were classified according to their location on SD-OCT: within the central 3 mm diameter of the macula, corresponding to the inner ring of the ETDRS grid (central macula), and in the outer retinal layers beyond the central 3 mm (perifoveal macula).