Table 1 of Alayed, Mol Vis 2025; 31:486-500.

Table 1. Gene candidates in which variants have been associated with FECD.

HGNC gene symbol Gene name OMIM number Cytogenetic location Transcript Genomic coordinates Strand
COL8A2 Collagen Type VIII Alpha 2 Chain 120252 1p34.3 NM_005202.4 chr1:36,560,840–36,590,823 -
SLC4A11 Solute Carrier Family 4 Member 11 610206 20p13 NM_001174089.2 chr20:3,208,068–3,219,836 -
ZEB1 Zinc Finger E-box Binding Homeobox 1 189909 10p11.22 NM_001174096.2 chr10:31,608,145–31,818,732 +
AGBL1 AGBL Carboxypeptidase 1 615496 15q25.3 NM_001386094.1 chr15:86,623,102–87,459,387 +
LOXHD1 Lipoxygenase Homology PLAT Domains 1 613072 18q21.1 NM_001384474.1 chr18:44,057,236–44,237,183 -

Genomic coordinates reported for the human reference genome are provided for build hg19. HGNC: Human Genome Organisation (HUGO) Gene Nomenclature Committee. OMIM: Online Mendelian Inheritance in Man database (https://www.omim.org/). The strand used for transcription, whether it is the sense (+) or the anti-sense (-) strand, is shown for each gene entry.

Alayed, Mol Vis 2025; 31:486-500. http://www.molvis.org/molvis/v31/486

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