Figure 2. Examples of multimodality images in three patients with achromatopsia. Patient 1 demonstrates central hyperautofluorescence of the fovea. A: Infrared (IR) shows a normal reflectivity pattern. B: OCT shows stippling of the ellipsoid zone. C: No outer segment loss or other abnormalities appear in the retinal layers. Patient 2 demonstrates a normal autofluorescence pattern. D: IR shows central foveal hyper-reflectance. E: OCT shows stippling of the ellipsoid zone. F: No outer segment loss or other abnormalities appear in the retinal layers. Patient 3 shows central foveal hypoautofluorescence with a hyperautofluorescent halo. G: IR shows hyper-reflectance at the fovea lesion. H: OCT demonstrates foveal outer retina atrophy with secondary choroidal hyperreflectivity. I: Retinal layers outside the fovea are well preserved.