Figure 2. At 48 h after infection of human retinal pigment epithelial cells (ARPE-19) with lentivirus at a multiplicity of infection (MOI) of 20, the mRNA expression of paired box gene 6 (PAX6) showed a significant downward trend ( n=3; PAX6-shRNA group versus NC-shRNA group; *p<0.05, **p<0.01, ***p<0.001).