Table 4 of
Sun, Mol Vis 2025; 31:33-43. Table 4 of
Sun, Mol Vis 2025; 31:33-43.
Table 4. The genes implicated in previous ROP studies.
| Gene | Gene product | Gene category | Reference (PMID) |
|---|---|---|---|
| SerpinF1 | Pigment epithelium derived factor | angiogenic | 18787502 |
| ALDH2 | Aldehyde dehydrogenase | angiogenic | 18787502 |
| IL1A | Interleukin 1A | inflammation | 18787502 |
| ILIB | Interleukin 1B | inflammation | 18787502 |
| TRAF2 | TNF-receptor-associated factor 2 | inflammation | 18787502 |
| NGF | Nerve growth factor | angiogenic | 30680928 |
| COX2 | cyclooxygenase 2 | inflammation | 12601017 |
| SOD | superoxide dismutase | antioxidant | 22574884 |
| BDNF | brain-derivated neurotrophic factor | angiogenic | 34346275 |
| NDP | Norrie disease protein | proliferative retinopathic diseases | 32884843 |
| FZD4 | frizzled-4 | proliferative retinopathic diseases | 32884843 |
| WIF1 | Wnt inhibitor factor 1 | proliferative retinopathic diseases | 35080047 |
| ATG5 | autophagy-related protein 5 | angiogenic | 31070476 |
| FOXC2 | forkhead box protein C2 | inflammation | 29380370 |