Figure 2. Representations of family trees. Family 1 (A), Family 2 (B), Family 3 (C), Family 4 (D), and Family 5 (E) are represented. Round symbols denote females, square symbols denote males; fully filled symbols indicate patients with congenital or juvenile glaucoma; unfilled symbols represent unaffected individuals; and symbols with a black dot inside correspond to unaffected individuals carrying genetic variants (observed only in Family 3).