Figure 5. CysLTR1 inhibition affects the TEER of EC and ARPE-19 monolayers. TEER (net resistance × 1.1 cm²) values of (A) EC and (B) ARPE-19 monolayers treated for 7 days with 100 nM MK, 1,000 nM MK, 100 nM ZK, or 1,000 nM ZK under standard and high-glucose conditions. Data are represented as bar graphs ± SDs, n = 2-3 (ECs) and n = 5 (ARPE-19). Repeated-measures two-way analysis of variance (main factors: treatment and glucose levels), followed by a Dunnett multiple comparison test, was performed. ***p < 0.0001 and **p < 0.01 for the single standard glucose group versus the single high-glucose group. $$p < 0.001 and $p < 0.05 for the single control group versus the single treatment group.