Table 2 of
Arslan, Mol Vis 2025; 31:142-157. Table 2 of
Arslan, Mol Vis 2025; 31:142-157.
Table 2. Equations of dissolution rate parameters in pharmacokinetic perspective.
| Parameter | Equation (Excel Formula Format) |
|---|---|
| Cmax, Maximum concentration in the vitreous part | =C0/(1-EXP(-ke*r)) |
| Half-life (T1/2), Time that passed for spending the NTB’s half of dose | =0.693/ke |
| Tmax, Time to attain maximum concentration for vitreous part | =LN(ka/ke)/(ka-ke) |
| MRT, mean residence time of the NTB substance molecules in the dosage form | =SUMPRODUCT(t_range, (100 - y_range))/SUM(100 - y_range) |
| DE, dissolution efficiency | =SUM(y_range)/(y100*t)*100 |