Figure 2 of Betts, Mol Vis 2024; 30:74-91.

Figure 2. Structure of the eye, showing key layers of the retina. Drusen-like deposits composed of accumulated lipid and protein deposits in Bruch’s membrane (BrM). The BrM also greatly thickens and increases the diffusion distance from the choroid to the retinal pigment epithelium (RPE).