Table 2 of
Gushansky, Mol Vis 2024; 30:489-496. Table 2 of
Gushansky, Mol Vis 2024; 30:489-496.
Table 2. Distribution of 167 dry eye disease cases regarding gastrointestinal medications among 1165 SARS-CoV-2 hospitalized patients.
| Drug (n=-/+) | Number (incidence) of patients with DED | p-value | |
|---|---|---|---|
| Antiemetics (dopamine antagonists) | |||
| Metoclopramide (1131/34) | 147 (13.0%) | 20 (58.8%) | <0.001 |
| Domperidone (1160/5) | 165 (14.2%) | 2 (40%) | 0.103 |
| Laxatives | |||
| Lactulose (1074/91) | 145 (13.5%) | 22 (24.2%) | 0.005 |
| Bisacodyl (1101/64) | 159 (14.4%) | 8 (12.5%) | 0.674 |
| Polyethylene glycol (1095/70) | 150 (13.7%) | 17 (24.3%) | 0.014 |
| Proton pump inhibitors (PPIs) | |||
| Omeprazole (684/481) | 120 (17.5%) | 47 (9.8%) | <0.001 |
| Lansoprazole (1138/27) | 167 (14.7%) | 0 (0%) | 0.032 |
| Esomeprazole (957/208) | 141 (14.7%) | 26 (12.5%) | 0.412 |
| Secondary bile acid | |||
| Ursodeoxycholic acid (1161/4) | 165 (14.2%) | 2 (50%) | 0.041 |