Table 5 of
Yadav, Mol Vis 2024; 30:434-446. Table 5 of
Yadav, Mol Vis 2024; 30:434-446.
Table 5. Logistic regression analysis of IL-6 (rs1800795, rs1800796, rs1800797) SNPs in control group and AMD patients.
| Model | Genotype | Control | Patient | OR (95% CI) | P value | AIC | BIC |
|---|---|---|---|---|---|---|---|
| rs1800795 | |||||||
| Codominant | G/G | 70 (70%) | 74 (56.5%) | 1 | 0.025 | 314.7 | 325 |
| G/C | 25 (25%) | 54 (41.2%) | 2.04 (1.15–3.63) | ||||
| C/C | 5 (5%) | 3 (2.3%) | 0.57 (0.13–2.46) | ||||
| Dominant | G/G | 70 (70%) | 74 (56.5%) | 1 | 0.035 | 315.6 | 322.5 |
| G/C-C/C | 30 (30%) | 57 (43.5%) | 1.80 (1.04–3.11) | ||||
| Recessive | G/G-G/C | 95 (95%) | 128 (97.7%) | 1 | 0.27 | 318.8 | 325.7 |
| C/C | 5 (5%) | 3 (2.3%) | 0.45 (0.10–1.91) | ||||
| Overdominant | G/G-C/C | 75 (75%) | 77 (58.8%) | 1 | 0.0094 | 313.3 | 320.2 |
| G/C | 25 (25%) | 54 (41.2%) | 2.10 (1.19–3.72) | ||||
| Log-additive | C | — | — | 1.43 (0.88–2.30) | 0.14 | 317.9 | 324.8 |
| rs1800796 | |||||||
| Codominant | G/G | 39 (39%) | 65 (49.6%) | 1 | 0.18 | 318.6 | 328.9 |
| G/C | 50 (50%) | 58 (44.3%) | 0.70 (0.40–1.20) | ||||
| C/C | 11 (11%) | 8 (6.1%) | 0.44 (0.16–1.18) | ||||
| Dominant | G/G | 39 (39%) | 65 (49.6%) | 1 | 0.11 | 317.5 | 324.4 |
| G/C-C/C | 61 (61%) | 66 (50.4%) | 0.65 (0.38–1.10) | ||||
| Recessive | G/G-G/C | 89 (89%) | 123 (93.9%) | 1 | 0.18 | 318.3 | 325.2 |
| C/C | 11 (11%) | 8 (6.1%) | 0.53 (0.20–1.36) | ||||
| Overdominant | G/G-C/C | 50 (50%) | 73 (55.7%) | 1 | 0.39 | 319.3 | 326.2 |
| G/C | 50 (50%) | 58 (44.3%) | 0.79 (0.47–1.34) | ||||
| Log-additive | C | — | — | 0.68 (0.45–1.03) | 0.064 | 316.6 | 323.5 |
| rs1800797 | |||||||
| Codominant | G/G | 77 (77%) | 72 (55%) | 1 | 0.009 | 308 | 318.3 |
| G/A | 17 (17%) | 51 (38.9%) | 3.21 (1.70–6.06) | ||||
| A/A | 6 (6%) | 8 (6.1%) | 1.43 (0.47–4.31) | ||||
| Dominant | G/G | 77 (77%) | 72 (55%) | 1 | 0.004 | 307.7 | 314.6 |
| G/A-A/A | 23 (23%) | 59 (45%) | 2.74 (1.54–4.90) | ||||
| Recessive | G/G-G/A | 94 (94%) | 123 (93.9%) | 1 | 0.97 | 320.1 | 326.9 |
| A/A | 6 (6%) | 8 (6.1%) | 1.02 (0.34–3.04) | ||||
| Overdominant | G/G-A/A | 83 (83%) | 80 (61.1%) | 1 | 0.002 | 306.4 | 313.3 |
| G/A | 17 (17%) | 51 (38.9%) | 3.11 (1.66–5.84) | ||||
| Log-additive | A | — | — | 1.92 (1.20–3.07) | 0.0048 | 312.1 | 319 |