Figure 6. PPARα agonist promotes corneal epithelial wound healing in WT mice. Representative slit-lamp images (A) and wound closure analysis (B) show that fenofibrate promotes corneal epithelial repair. Representative immunofluorescence staining (C), intensity analysis (D), and mRNA expression (E) shows that fenofibrate increases PPARα expression during corneal epithelial repair. Representative immunofluorescence staining (F), intensity analysis (G), and mRNA expression (H) demonstrate that fenofibrate increases Ki67 expression during corneal epithelial repair. Data are shown as mean ± SD n=6–8, **p<0.01, ***p<0.001. Scale bars: 50 μm (C), Scale bars: 100 μm (F). Fe, Fenofibrate.