Figure 2. Imaging studies from three subjects with NCMD. A-C images correspond to a female patient from the first affected generation (I-2). D-F images correspond to a male patient from the second affected generation (II-1). F-H images correspond to a child from the third affected generation (III-1). A, D, and G: Fundus photographs showing colobomatous-like atrophic chorioretinal central macular lesions. B, E: Autofluorescence imaging showing central macular hypoautofluourescence with a surrounding hyperautofluorescence halo. C, F, and H: Optical coherence tomography (OCT) images showing loss of organization of internal and external retinal layers, with lacunae in C and F.