Table 7 of Novo, Mol Vis 2024; 30:348-367.


Table 7. Representative lens marker changes in human equatorial LECs after culture.

Gene code Gene name Equatorial FPKM Equatorial FPKM Fold change FDR
LGSN Lengsin 4.6 0.07 −66 7.7E-7
CRYGD Gamma D crystallin 10.1 0.2 −56 1.7E-6
SFRP2 Secreted frizzled-related protein 2 310 10 −31 2.3E-34
FGFR3 FGF receptor 3 209 13 −16 7.5E-40
FOXE3 Forkhead Box E3 375.02 26 −14 3.4E-21
HSF4 Heat shock Factor 4 4.4 0.4 −10 4.7E-7
FGFR2 FGF receptor 2 36 4 −9 2.9E-31
CITED2 Cbp/p300 Interacting Transactivator with Glu/Asp Rich Carboxyl-Terminal Domain 2 214.44 32.41 −6.6 2.25E-17
COL4A3 Collagen Type IV Alpha 3 Chain 62.30 9.83 −6.34 3.50E-11
AQP5 Aquaporin 5 103.53 19.17 −5.40 1.82E-3
HSPG2 Heparan Sulfate Proteoglycan 2 90.43 26.32 −3.44 4.16E-5
CRYAB Crystallin Alpha B 5130.63 1501.50 −3.42 2.68E-8
SIX3 SIX Homeobox 3 93.56 28.24 −3.31 3.11E-12
PAX6 Paired Box 6 42.86 16.23 −2.64 2.27E-5
AQP1 Aquaporin 1 607.53 252.96 −2.40 1.11E-2