Table 5 of
Novo, Mol Vis 2024; 30:348-367. Table 5 of
Novo, Mol Vis 2024; 30:348-367.
Table 5. Genes with the largest fold change in expression in aged human equatorial epithelial cells following 24 h of culture. Those with known roles in inflammation and/or innate immunity are in bold font.
| Gene code | Gene name | Equatorial FPKM | Equatorial FPKM | Fold change | FDR |
|---|---|---|---|---|---|
| MMP1 | Matrix Metallopeptidase 1 | 0.00 | 94.34 | 29,959.76 | 5.10E-14 |
| PTGS2 | Prostaglandin-Endoperoxide Synthase 2 | 0.00 | 33.92 | 21,579.19 | 7.97E-5 |
| CSF3 | Colony Stimulating Factor 3 | 0.00 | 83.00 | 21,371.37 | 2.29E-129 |
| MMP3 | Matrix Metallopeptidase 3 | 0.00 | 91.09 | 19,587.73 | 1.46E-11 |
| IL13RA2 | Interleukin 13 Receptor Subunit Alpha 2 | 0.00 | 74.80 | 14,107.77 | 1.01E-40 |
| CXCL8 | C-X-C Motif Chemokine Ligand 8 | 0.06 | 576.41 | 9537.83 | 4.16E-60 |
| LAMC2 | Laminin Subunit Gamma 2 | 0.06 | 535.19 | 8279.12 | 4.81E-14 |
| MMP10 | Matrix Metallopeptidase 10 | 0.01 | 104.99 | 5537.03 | 9.77E-67 |
| CLMP | CXADR like Membrane Protein | 0.00 | 9.32 | 5467.92 | 8.49E-10 |
| FGF5 | Fibroblast Growth Factor 5 | 0.00 | 7.74 | 5350.30 | 1.10E-26 |
| MMP9 | Matrix Metallopeptidase 9 | 0.00 | 19.05 | 5161.34 | 1.80E-4 |
| CDCP1 | CUB Domain Containing Protein 1 | 0.00 | 6.79 | 5127.52 | 3.76E-8 |
| CD93 | CD93 Molecule | 0.00 | 6.08 | 4708.85 | 6.57E-9 |
| C2CD4A | C2 Calcium Dependent Domain Containing 4A | 0.00 | 10.64 | 4250.85 | 5.21E-12 |
| ESM1 | Endothelial Cell Specific Molecule 1 | 0.01 | 48.83 | 3984.72 | 3.25E-14 |
| RCSD1 | RCSD Domain Containing 1 | 0.00 | 4.08 | 3863.62 | 1.09E-9 |
| BNC1 | Basonuclin 1 | 0.00 | 6.47 | 3681.52 | 1.47E-9 |
| RHCG | Rh Family C Glycoprotein | 0.00 | 12.22 | 3661.28 | 6.15E-10 |
| CXCL1 | C-X-C Motif Chemokine Ligand 1 | 0.26 | 857.96 | 3235.67 | 3.10E-10 |
| FSRL1 | F2R like Trypsin Receptor 1 | 0.00 | 9.46 | 3215.99 | 7.38E-44 |