Table 4 of Novo, Mol Vis 2024; 30:348-367.


Table 4. Representative genes highly expressed (top 10%) in both aged human equatorial epithelial cells and 24 month old mouse lens epithelial cells.

Gene code Gene name Equatorial human FPKM Mouse FPKM References
CRYBB2/Crybb2 Crystallin Beta B2 9219.07 16,373.51 [96]
CRYAB/Cryab Crystallin Alpha B 5739.75 9504.28 [95]
ALDH1A1/Aldh1a1 Aldehyde Dehydrogenase 1 Family Member A1 1464.38 234.90 [108]
VIM/Vim Vimentin 871.48 1257.50 [70,109]
CRYGS/Crygs Crystallin Gamma S 863.88 2602.04 [110]
CRIM1/Crim1 Cysteine Rich Transmembrane BMP Regulator 1 560.18 676.14 [112]
FOXE3/Foxe3 Forkhead Box E3 420.07 261.49 [101]
CRYAA/Cryaa Crystallin Alpha A 300.71 18,617.30 [98]
SPARC/Sparc Secreted Protein Acidic and Cysteine Rich 193.81 703.63 [113]
BFSP1/Bfsp1 Beaded Filament Structural Protein 1 86.67 662.61 [114]
DKK3/Dkk3 Dickkopf 3 79.58 1128.94 [115]
COL4A2/Col4a2 Collagen Type IV Alpha 2 Chain 44.07 735.50 [102]