Table 3 of Novo, Mol Vis 2024; 30:348-367.


Table 3. Examples of genes highly expressed (top 10%) in both aged human central epithelial cells and 24 month old mouse lens epithelial cells.

Gene code Gene name Central
human FPKM Mouse
FPKM References
CRYAB/Cryab Crystallin Alpha B 3222.44 9608.55 [95]
CRYBB2/Crybb2 Crystallin Beta B2 2205.12 16,545.00 [96]
ALDH1A1/Aldh1a1 Aldehyde Dehydrogenase Family 1, Subfamily A1 1612.38 237.60 [108]
VIM/Vim Vimentin 1124.82 1271.65 [70,109]
CRIM1/Crim1 Cysteine Rich Transmembrane MBP Regulator 1 543.42 683.85 [108]
CRYGS/Crygs Crystallin, Gamma S 481.65 2628.69 [110]
AQP1/Aqp1 Aquaporin 1 450.93 80.43 [73]
CCN2/Ccn2 Cellular Communication Network Factor 2 387.64 182.95 [111]
CRYAA/Cryaa Crystallin Alpha A 362.02 18,815.73 [98]
CITED2/Cited2 Cbp/p300-Interacting Transactivator with Glu/Asp-Rich C-terminal Domain 2 255.61 46.77 [100]
FOXE3/Foxe3 Forkhead Box E3 244.40 264.49 [101]
COL4A3/Col4a3 Collagen Type IV Alpha 3 128.13 165.46 [102]