Table 2 of
Novo, Mol Vis 2024; 30:348-367. Table 2 of
Novo, Mol Vis 2024; 30:348-367.
Table 2. Examples of genes known to be important for lens biology that are highly expressed in both the central and equatorial human lens epithelium freshly isolated from cadaver lenses.
| Gene code | Gene name | Central FPKM | Equatorial FPKM | References |
|---|---|---|---|---|
| CRYAB | Crystallin Alpha B | 2929.52 | 5271.15 | [95] |
| CRYBB2 | Crystallin Beta B2 | 2012.33 | 8481.76 | [96] |
| VIM | Vimentin | 1025.50 | 800.17 | [70] |
| FTL | Ferritin Light Chain | 572.87 | 550.88 | [97] |
| AQP1 | Aquaporin 1 | 409.85 | 624.03 | [73] |
| CRYAA | Crystallin Alpha A | 332.91 | 274.72 | [98] |
| GJA1 | Gap Junction Protein Alpha 1 | 270.28 | 119.79 | [99] |
| CITED2 | Cbp/p300 Interacting Transactivator with Glu/Asp rich carboxyl-terminal domain 2 | 232.53 | 220.31 | [100] |
| FOXE3 | Forkhead box E3 | 222.00 | 385.26 | [101] |
| COL4A3 | Collagen Type IV Alpha 3 Chain | 116.46 | 63.98 | [102] |
| AQP5 | Aquaporin 5 | 82.39 | 106.34 | [103] |
| SIX3 | SIX homeobox 3 | 78.04 | 96.13 | [104] |
| HSPG2 | Heparan Sulfate Proteoglycan 2 | 71.18 | 92.89 | [105] |
| PAX6 | Paired Box 6 | 44.26 | 44.03 | [67] |
| ITGB1 | Integrin Subunit Beta 1 | 23.23 | 29.17 | [106,107] |