Figure 2 of Novo, Mol Vis 2024; 30:348-367.


Figure 2. Advaita iPathway analysis of differentially expressed pathways/genes between central lens epithelial compared to equatorial epithelial. A: Bar graph showing the “differentially expressed pathway genes on calcium signaling pathway (p-value 1.65E-6) expressed more highly in the 0H human equatorial LECs. B: Bar graph showing the “differentially expressed genes annotated to epithelial cell proliferation” (p value 3.600E-4) expressed more highly in the 0H human equatorial LECs. C: Bar graph showing the “differentially expressed genes annotated with cell adhesion” (p value 4.400E-18) expressed more highly in the 0H human equatorial LECs. D: Bar graph showing the “differentially expressed genes annotated with cell junction assembly” (p value 8.700E-8) expressed more highly in the 0H human equatorial LECs. E: Bar graph showing the “differentially expressed genes annotated with cation transport” (p value 2.500E-8) expressed more highly in the 0H human equatorial LECs. Red bars are genes that are expressed more highly in the equatorial lens epithelial cells compared to central lens epithelial cells. Blue bars are genes that are expressed more highly in central lens epithelial cells compared to equatorial lens epithelial cells.