Table 3 of Altankhuyag, Mol Vis 2024; 30:320-335.

Table 3. Association between allele frequencies of SNPs and AMD.

Gene refSNP ID Alleles Location AAC Risk allele RAF cOR 95%CI p value Power
Case Control
n=322 n=446
ARMS2 rs10490924 T/G Exon Ala/Ser T 0.714 0.473 2.78 2.05-3.77 <.001 100%
CFH rs1061170 T/C Exon Tyr/His C 0.245 0.15 1.84 1.28-2.64 0.001 90.70%
CFH rs1065489 G/T Exon Glu/Asp G 0.634 0.513 1.64 1.22-2.20 0.001 91.80%
CFH rs800292 A/G Exon Ile/Val G 0.472 0.336 1.76 1.31-2.37 <.001 96.80%
VEGF-A rs833061 T/C Upstream - C 0.295 0.274 1.11 0.81-1.53 0.514 9.40%
VEGF-A rs1413711 C/T Intron - C 0.686 0.661 1.12 0.82-1.52 0.468 10.80%
VEGF-A rs2010963 C/G 5` UTR - G 0.373 0.327 1.22 0.90-1.65 0.193 26.30%
VEGF-A rs144854329 Del/Ins Upstream - Del 0.702 0.688 1.07 0.78-1.46 0.688 6.10%
VEGF-A rs2146323 C/A Intron - C 0.702 0.668 1.17 0.86-1.59 0.322 16.70%
VEGF-A rs1570360 G/A Intron - G 0.826 0.785 1.3 0.90-1.88 0.157 28.80%

Note: The values were given as frequency. p value by two-tailed Chi square (x2) test for 2x4 contingency table. Odds ratio and confidence interval was calculated by logistic regression. Abbreviations: AAC, Amino acid change; RAF, Risk allele frequency; cOR, Crude odds ratio; aOR, Adjusted odds ratio; CI, Confidence interval.

Altankhuyag, Mol Vis 2024; 30:320-335. http://www.molvis.org/molvis/v30/320

©2024 Molecular Vision http://www.molvis.org/molvis/

ISSN 1090-0535