Figure 4. Cav1 regulates the NLRP3 pathway. Retinal endothelial cells (RECs) grown in normal glucose (NG), high glucose (HG), HG+Cav1 siRNA (Cav1 siRNA), and HG+scrambled siRNA (HG+Sc). Panel A shows NLRP3, Panel B shows cleaved caspase 1, and Panel C shows IL-1β protein levels. Arbitrary units (A.U.); *p <.05 versus NG; #p <.05 versus HG; n = 5. Data are mean±SEM.