Figure 3. Cav1 regulates HMGB1 and TNFα. Retinal endothelial cells (REC) grown in normal glucose (NG), high glucose (HG), HG+Cav1 siRNA (Cav1 siRNA), and HG+scrambled siRNA (HG+Sc). Panel A shows HMGB1, and Panel B shows TNFα protein levels. Arbitrary units (A.U.); *p <.05 versus NG; #p <.05 versus HG; n = 5. Data are mean±SEM.