Figure 2. Partial nucleotide sequences of exon 4 of the TGFBI gene in affected and unaffected family members.: A, patient 1 had a homozygous mutation of p. R124H in the fourth exon of the TGFBI gene; B, Patients 2 had a heterozygous mutation of p. R124H (CGC>CAC) in the fourth exon of the TGFBI gene; C, Patient 3 had a heterozygous mutation of p. R124H (CGC>CAC) in the fourth exon of the TGFBI gene; D, Patient 4 had no mutation in the fourth exon of the TGFBI gene.