Table 3 of Cehofski, Mol Vis 2024; 30:17-35.

Table 3. Significantly regulated proteins ordered according to fold change.

Protein ID Protein names Gene names p-value Fold change
DME/control
P02671 Fibrinogen alpha chain FGA 1.49×10−6 17.8
P02675 Fibrinogen beta chain FGB 8.19×10−7 15.8
P02679 Fibrinogen gamma chain FGG 2.26×10−7 12.2
P02656 Apolipoprotein C-III APOC3 0.000177 6.40
P00738 Haptoglobin HP 0.054 3.81
P18428 Lipopolysaccharide-binding protein LBP 1.3×10−8 3.65
P06727 Apolipoprotein A-IV APOA4 1.03×10−6 3.56
P02751 Fibronectin FN1 2.5×10−6 2.96
P06312 Ig kappa chain V-IV region IGKV4–1 0.0025 2.95
P02760 Protein AMBP AMBP 0.0017 2.85
Q14624 Inter-alpha-trypsin inhibitor heavy chain H4 ITIH4 3.45×10−5 2.71
P02750 Leucine-rich alpha-2-glycoprotein LRG1 0.0022 2.52
P02647 Apolipoprotein A-I APOA1 0.00064 2.51
P19827 Inter-alpha-trypsin inhibitor heavy chain H1 ITIH1 9.84×10−5 2.42
P01031 Complement C5 C5 0.00051 2.41
P27169 Serum paraoxonase/arylesterase 1 PON1 0.00059 2.38
P01876 Ig alpha-1 chain C region IGHA1 6.19×10−5 2.34
P19823 Inter-alpha-trypsin inhibitor heavy chain H2 ITIH2 0.00014 2.29
P04004 Vitronectin VTN 0.00040 2.29
P00734 Prothrombin F2 0.0080 2.16
P08603 Complement factor H CFH 0.00014 2.12
P05546 Heparin cofactor 2 SERPIND1 0.00055 2.11
P08697 Alpha-2-antiplasmin SERPINF2 0.0017 2.09
P0C0L5 Complement C4-B C4B 0.0032 2.06
P02748 Complement component C9 C9 0.015 2.04
A0A075B6J9   IGLV2–18 0.0044 2.03
P01042 Kininogen-1 KNG1 0.00074 1.92
P04180 Phosphatidylcholine-sterol acyltransferase LCAT 0.0041 1.92
P01024 Complement C3 C3 6.02×10−5 1.90
P01008 Antithrombin-III SERPINC1 0.0015 1.90
P03952 Plasma kallikrein KLKB1 0.0029 1.89
P10643 Complement component C7 C7 0.0021 1.88
P13671 Complement component C6 C6 0.0019 1.87
P07360 Complement component C8 gamma chain C8G 0.0054 1.84
P04432 Ig kappa chain V-I region Daudi IGKV1–12 0.045 1.78
P25311 Zinc-alpha-2-glycoprotein AZGP1 0.00054 1.78
P01011 Alpha-1-antichymotrypsin SERPINA3 0.0041 1.77
P08185 Corticosteroid-binding globulin SERPINA6 0.011 1.75
P05543 Thyroxine-binding globulin SERPINA7 0.021 1.75
P43652 Afamin AFM 0.018 1.75
P01009 Alpha-1-antitrypsin SERPINA1 0.0014 1.74
P06681 Complement C2 C2 0.0037 1.70
P26927 Hepatocyte growth factor-like protein MST1 0.0056 1.68
P02753 Retinol-binding protein 4 RBP4 0.0051 1.68
P04217 Alpha-1B-glycoprotein A1BG 0.0095 1.65
P51884 Lumican LUM 0.0015 1.55
P07357 Complement component C8 alpha chain C8A 0.012 1.54
Q96PD5 N-acetylmuramoyl-L-alanine amidase PGLYRP2 0.019 1.54
P08571 Monocyte differentiation antigen CD14 CD14 0.00066 1.54
P01023 Alpha-2-macroglobulin A2M 0.016 1.53
P01019 Angiotensinogen AGT 0.014 1.50
P0DOY3 Ig lambda-6 chain C region IGLC6 0.0067 1.48
P04196 Histidine-rich glycoprotein HRG 0.019 1.44
P02790 Hemopexin HPX 0.013 1.39
P00450 Ceruloplasmin CP 0.00096 1.35
Q96KN2 Beta-Ala-His dipeptidase CNDP1 0.024 0.66
Q92520 Protein FAM3C FAM3C 0.012 0.64
Q14118 Dystroglycan DAG1 0.037 0.60
P23471 Receptor-type tyrosine-protein phosphatase zeta PTPRZ1 0.010 0.60
Q9HCB6 Spondin-1 SPON1 0.019 0.60
P13591 Neural cell adhesion molecule 1 NCAM1 0.0063 0.60
P08294 Extracellular superoxide dismutase [Cu-Zn] SOD3 0.026 0.60
P07195 L-lactate dehydrogenase B chain LDHB 0.038 0.59
Q9BU40 Chordin-like protein 1 CHRDL1 0.0060 0.59
Q12860 Contactin-1 CNTN1 0.024 0.58
Q12805 EGF-containing fibulin-like extracellular matrix protein 1 EFEMP1 0.0042 0.57
Q92823 Neuronal cell adhesion molecule NRCAM 0.012 0.56
Q9UHL4 Dipeptidyl peptidase 2 DPP7 0.0040 0.55
Q86UX2 Inter-alpha-trypsin inhibitor heavy chain H5 ITIH5 0.048 0.52
P10599 Thioredoxin TXN 0.013 0.52
P35555 Fibrillin-1 FBN1 0.011 0.52
Q9Y4C0 Neurexin-3 NRXN3 0.0038 0.52
Q08554 Desmocollin-1 DSC1 0.038 0.51
P31025 Lipocalin-1 LCN1 0.048 0.51
Q06481 Amyloid-like protein 2 APLP2 0.028 0.50
Q14767 Latent-transforming growth factor beta-binding protein 2 LTBP2 0.0035 0.50
Q9P121 Neurotrimin NTM 0.0052 0.50
P30086 Phosphatidylethanolamine-binding protein 1 PEBP1 6.77×10−5 0.49
P98164 Low-density lipoprotein receptor-related protein 2 LRP2 0.025 0.49
P98160 Basement membrane-specific heparan sulfate proteoglycan core protein HSPG2 0.030 0.47
P62987 Ubiquitin-60S ribosomal protein L40 UBA52 0.0061 0.45
Q08629 Testican-1 SPOCK1 0.014 0.45
P06733 Alpha-enolase ENO1 0.012 0.44
P09972 Fructose-bisphosphate aldolase C ALDOC 0.0013 0.42
Q08380 Galectin-3-binding protein LGALS3BP 0.037 0.41
P00338 L-lactate dehydrogenase A chain LDHA 0.030 0.41
P78509 Reelin RELN 0.052 0.39
P14618 Pyruvate kinase PKM PKM 0.0027 0.38
P07737 Profilin-1 PFN1 0.012 0.38
Q02413 Desmoglein-1 DSG1 0.0029 0.37
P23528 Cofilin-1 CFL1 0.054 0.36
O00468 Agrin AGRN 0.00097 0.34
P11021 78 kDa glucose-regulated protein HSPA5 0.032 0.34
Q9NZT1 Calmodulin-like protein 5 CALML5 0.058 0.30
P31151 Protein S100-A7 S100A7 0.043 0.29
P00558 Phosphoglycerate kinase 1 PGK1 0.00026 0.25
P63104 14–3-3 protein zeta/delta YWHAZ 0.010 0.24
P22914 Beta-crystallin S CRYGS 0.0060 0.23
P04075 Fructose-bisphosphate aldolase A ALDOA 0.00062 0.19
P15924 Desmoplakin DSP 0.014 0.18
P48594 Serpin B4 SERPINB4 0.040 0.12

Cehofski, Mol Vis 2024; 30:17-35. http://www.molvis.org/molvis/v30/17

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