Figure 4. Opacification of lens proteins by m-calpain

In vitro light scattering in the lens soluble proteins from rats of 12, 18, and 28 days of age caused by incubating with m-calpain (Shearer and Shih, unpublished data). Note that this in vitro effect is attenuated with age as occurs with the selenite cataract. The vertical axis is change in optical density at 405 nm.