Figure 7 of
Boatright, Mol Vis 3:15, 1997.
Figure 7. Effect of transversion mutations of Ret-1/PCE-I or the CRX-binding element on reporter gene activity.
A -70 to +101 fragment of the IRBP gene was inserted into pBLCAT3 (p70; "Wild Type") with or without transversion mutations of the two proposed cis elements. Mutation of either sequence significantly inhibited CAT activity (p < 0.05), though not to background. The data are from two experiments. Activities are means ± SEM of percentage of Wild Type from individual experiments. Sample size is indicated in parentheses above error bars.