Tables for
Mol Vis 3:1, 1997.Tables for
Mol Vis 3:1, 1997.
Table 1. Two point LOD scores of MCDR1 linked markers versus the macular dystrophy in the French family
Marker theta
0 0.1 0.2 0.3 0.4 Zmax theta max
D6S251 3.0 2.5 1.9 1.4 0.7 3.0 0.0
D6S275 1.0 1.2 1.0 0.7 0.4 1.2 0.08
D6S361 0.6 0.4 0.2 0.1 0.02 0.6 0.0
D6S492 0.13 0.1 0.09 0.06 0.04 0.1 0.0
D6S424 -0.4 2.8 2.4 1.7 0.9 2.9 0.07
D6S300 -2.3 1.5 1.4 1.0 0.5 1.5 0.12
D6S1682 -0.4 0.4 0.5 0.4 0.2 0.5 0.2
D6S501 1.8 1.4 0.9 0.5 0.1 1.8 0.0
D6S249 0.06 0.05 0.03 0.01 0.00 0.06 0.01
GATAp6995 1.7 1.2 0.8 0.3 0.03 0.01 0.0
afm270xe5 1.4 1.2 0.8 0.5 0.2 0.05 0.0
D6S1716 0.8 0.9 0.7 0.4 0.08 0.9 0.05
D6S1717 4.5 3.6 2.7 1.6 0.7 4.5 0.0
D6S1565 1.3 1.6 1.4 1.0 0.5 1.6 0.08
GATAp9365 -2.1 1.7 1.5 1.1 0.5 1.7 0.11
D6S1671 -15 -0.9 0.0 0.03 0.02 0.03 0.34
D6S475 3.4 2.7 1.9 1.2 0.5 3.4 0.0
D6S468 0.2 0.9 0.9 0.8 0.4 0.9 0.17
D6S283 -3.5 0.14 0.5 0.4 0.3 0.5 0.2
D6S301 -6.3 -1.0 -0.6 -0.3 -0.1 0.03 0.4
Zmax is the maximum LOD score achieved and the theta max is the genetic distance at which that maximum LOD score is achieved.
Table 2. Meiotic breakpoint analysis
Individual # 3008 5411 3030 3004 Marker D6S251 UI I UI UI D6S275 I UI UI UI D6S361 UI UI UI UI D6S492 UI UI UI UI D6S424 X I I I D6S300 I I I UI D6S1682 UI UI UI UI D6S501 I UI I UI D6S249 UI UI UI UI GATAp6995 I UI I UI afm270xe5 UI UI I I D6S1716 UI UI I I D6S1717 I I I I D6S1565 I UI UI UI GATAp9365 I UI I I D6S1671 UI X X X D6S475 I UI UI UI D6S468 UI X UI UI D6S283 UI UI UI UI D6S301 UI UI UI UI
Legend for Table 2
UI = uninformative
I = informative, phase known
X = fully infomative crossover