Figure 1. Antiangiogenic effect of ZK002 on alkali burn induced corneal neovascularization. A: Representative slit-lamp stereomicroscopic appearance of SD rat eyes on days 7, 10, and 14 with or without ZK002 or anti-vascular endothelial growth factor treatment. Panels B and C present images immediately after the alkali burn (C: corneal fluorescein staining), and Panel A presents the normal cornea. B: The percentage of corneal neovascular area (CorNV, %) was determined (n=7 per group) in the three groups on days 7, 10, and 14. Values are expressed as the mean ± standard error of the mean. Data were analyzed using ANOVA. A value of p < 0.05, was considered statistically significant.