Figure 13. HMGECs were differentiated for 48 h before exposure to combined latanoprost-BAK for 3 h. Lipid extracts were analyzed by ESI-MSMSALL (see Methods). Only the TAGs that reached significance are shown. Thirteen of 121 TAGs (10.7%) were significantly different
between latanoprost alone, BAK alone, and combined latanoprost-BAK. However, there were no TAGs that showed significant differences
between the combined latanoprost-BAK and each component in isolation. TAGs are labeled by two numbers corresponding to the
total number of carbons and the total number of double bonds, respectively. The fatty acid in parentheses represents one of
the three fatty acids of the parent TAG molecule. There were four replicates per condition. BAK: benzalkonium chloride; CE:
cholesteryl esters; Gray bar: p ≤ 0.05; Black bar: p ≤ 0.01; Dashed bar: p ≤ 0.001.
